RESEARCH ARTICLE
SLE Thrombocytopenia: From Peripheral Platelet Destruction to Central Hemopoietic Defect
Panayiotis D. Ziakas *
“Hygeia” Diagnostic & Therapeutic Centre. 9 Erythrou Stavrou St. 151 23 Athens, Greece
Article Information
Identifiers and Pagination:
Year: 2008Volume: 2
First Page: 111
Last Page: 118
Publisher Id: TOHJ-2-111
DOI: 10.2174/1874276900802010111
Article History:
Received Date: 25/09/2008Revision Received Date: 07/10/2008
Acceptance Date: 09/10/2008
Electronic publication date: 30/10/2008
Collection year: 2008
© 2008 Ziakas et al.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Thrombocytopenia in Systemic Lupus Erythematosus is a common clinical manifestation affecting up to one third of patients in published cohorts. Antiplatelet antibodies, antithrombopoietin antibodies and faulty hemopoiesis have been implicated among other immunologic and non-immunologic causes. This mini review is an uptodate summary of these immunologic phenomena.