RESEARCH ARTICLE
Features of Chronic Active Epstein-Barr virus Infection and Related Human Diseases
Motohiko Okano*
Center for Infectious Diseases Control, Hokkaido Institute of Public Health, North 19 West 12, Kita-ku,
Sapporo 060-0819, Japan.
Article Information
Identifiers and Pagination:
Year: 2011Volume: 5
First Page: 1
Last Page: 3
Publisher Id: TOHJ-5-1
DOI: 10.2174/1874276901105010001
Article History:
Received Date: 02/11/2010Revision Received Date: 16/11/2010
Acceptance Date: 19/11/2010
Electronic publication date: 01/02/2011
Collection year: 2011
© 2011 Motohiko Okano et al.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
A chronic undefined illness characterized by infectious mononucleosis (IM)-like symptoms and signs, possibly associated with Epstein-Barr virus (EBV) infection, designated as so-called chronic active EBV infection (CAEBV), is focused and discussed in this mini-review. Patients with CAEBV often develop T cell lymphoproliferative disorder (LPD)/lymphoma or NK cell LPD/lymphoma. Unique manifestations with generally poor prognosis of the disease prompt us to understand in particular the entity, diagnosis and treatment.
Keywords: CAEBV, diagnosis, treatment..